Difference between revisions of "Main Page"

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(Muscle project)
(Publications of the project)
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* ...
 
* ...
 
* Model validation
 
* Model validation
 
= Publications of the project =
 
* [https://dx.doi.org/10.1093%2Fnar%2Fgky1128 GTRD: a database on gene transcription regulation]
 
* [https://doi.org/10.17537/2019.14.373 Modular Visual Model of Energy Metabolism in Human Skeletal Muscle]
 
* [https://doi.org/10.17537/2020.15.20 A mathematical model linking signalling pathway and gene expression regulation in Human Skeletal Muscle]
 
* [http://ceur-ws.org/Vol-2569/short1.pdf Integrated Modular Model Linking Metabolism, Signaling Transduction and Gene Expression Regulation in Human Skeletal Muscle.]
 
* [https://doi.org/10.1038/s41598-020-60578-2 Regulation of Proteins in Human Skeletal Muscle: The Role of Transcription]
 
* [https://doi.org/10.3390/ijms22031208 Transcriptomic Signatures and Upstream Regulation in Human Skeletal Muscle Adapted to Disuse and Aerobic Exercise]
 
* Genome-wide atlas of promoters expression reveals contribution of transcribed regulatory elements to genetic control of disuse-mediated atrophy, under review
 
 
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Revision as of 14:58, 4 March 2021

Muscle project

...some intro/description ..

General scheme of the project

Project general scheme


Experiments

Rat

..experiment description ..


Human

..experiment description ..


Bioinformatic analysis

Human data analysis

  • Differentially expressed genes
  • Ontology analysis

CAGE-seq analysis

Mathematical modelling

Linkage of metabolic pathways and gene expression

Pathways and key proteins

Models

Integrated modular models

  • ...
  • Model validation